What is histamine intolerance?
Histamine is a substance that is produced in the body when a Amino acid is dismantled. It used to be thought that histamine only plays a role in allergic reactions, as it is mainly released by mast cells during allergic processes. Today, however, we know that it also has other functions. Histamine enables communication between nerve cells, for example, and is therefore important for neurotransmission. It is only present in the body for a short time, between 10 and 60 minutes.
What causes histamine intolerance?
Histamine intolerance in humans and animals is not caused directly by high levels of histamine in food, contrary to popular belief, but by the presence of another substance. This is used as a flavour enhancer in the form of free amino acids utilised.
In the body, the DAO enzyme the cadaverine produced from ingested lysine. Because cadaverine is very toxic, it takes precedence and prevents the breakdown of histamine. The body tries to excrete cadaverine as quickly as possible, leaving a large amount of histamine in the body.
Lysine is found as a free amino acid in many processed foods such as crisps, snacks, etc.
> More about the causes of histamine intolerance <.
What hinders the treatment of histamine intolerance?
It is often recommended to avoid foods with a high histamine content. This can alleviate the symptoms, but does not solve the problem.
LPS bacteria
Harmful LPS bacteria in the intestinal microbiome are a cause of histamine intolerance.
Lysine, which is present in the body in the form of free amino acids, produces cadaverine, which damages the mast cells that produce histamine.
Pesticide residues
Another cause of histamine intolerance is the blockade of the enzyme DAO (cytochrome P450) by the herbicide Glyphosate. In the body, the cadaverine produced from ingested lysine is broken down by the enzyme DAO.
Histamine intolerance treatment
Avoid genetically modified foods and meat from animals reared on genetically modified feed. These can negatively affect our intestinal flora and impair the function of the DAO enzyme in the intestine, which leads to a short-term overproduction of histamine.
The treatment for histamine intolerance is to rid the microbiome of the LPS bacteria present. Avoid foods that contain lysine as a free amino acid. Avoid industrially produced pork and poultry raised almost exclusively on industrial feed containing lysine.
Fulvicherb-Synergy with Fulvic acid helps to restore the intestinal microbiome and thus to treat histamine sensitivity.
English (UK) 
Deutsch 
Italiano 
Français 
Español 
Polski 
Slovenčina 
Slovenščina 
Čeština 
Română 