The role of free amino acids in the diet

It is known that the amino acids arginine and lysine are antagonists in absorption due to their almost identical structure.

In this article it was mentioned that animals fed with modern feed suffer from a number of diseases that also occur in humans. One of the causes of the aforementioned diseases is the content of free amino acids in the feed.

How are amino acids produced?

The amino acid threonine is produced by genetically modified E. coli bacteria. Their by-product is a single-cell protein (SCP), which has become a raw material for animal feed. This means that we feed the toxins of the heat-destroyed E. coli bacteria to the animals. It has a high crude protein content, an ideal amino acid structure and in principle corresponds to the desired, optimum protein content. But in this structure it is actually poisonous!

Imbalance and antagonism of amino acids

Two very interesting biological laws are amino acid antagonism and amino acid imbalance. It is known that Arginine and lysine are antagonists in terms of absorption due to their almost identical structure (both are two basic amino acids). In the living organism, a lack of arginine prevents the formation of blood vessels (angiogenesis). For example, it has been shown that lysine as a free amino acid in the feed of laying hens leads to a localised arginine deficiency (angiogenesis takes place, if at all, in the egg during hatching and embryonic development).

The high content of lysine, which occurs as a free amino acid in the feed of breeding hens, is therefore the main cause of hatching defects. The brood cannot break the eggshell, as the embryo's need for calcium, macro- and micronutrients remains in the eggshell.

Too much lysine amino acid in animal feed

Such quantities of lysine are not necessary, as most of it cannot be absorbed. Under natural conditions, the content of free amino acids in the intestine is low. Just like monosaccharides (simple sugars) such as Fructose or glucose only occur naturally in very small quantities. In order for lysine to be absorbed as a free amino acid, a sufficient quantity of so-called membrane transporter proteins is required, but these are only available in limited quantities.

Lysine-arginine antagonism leads to disturbances in cellular immunity, smooth muscle and Circulation. This leads to Kidney diseasesdelayed wound healing and many other serious causal relationships.

We had the opportunity to carry out trials with GM soya and lysine-free feed in several countries, and the result was always the same: if you feed functional, non-GM soya, there are no circulatory problems, no ear death in the animals, etc. Chickens that do not eat lysine grow up healthy. Chickens that do not eat lysine grow up healthy. In retrospect, you can see how poorly the epiphysis is supplied with blood in perosis because the blood vessels are not developed. Young chickens have necrosis of the femoral head, growing pigs have osteoporosis.

In the trials, we fed the pigs fishmeal, reduced the amount of lysine in the feed, omitted the genetically modified soya and solved the problems.

Chickens reared and processed with functional feed have intact internal organs, heart, liver, kidneys, an intact digestive and immune system and healthy, edible meat.

The constant availability of arginine is very important for a well-functioning immune system. This functional feeding offers the possibility of producing antibiotic-free pork and poultry meat, as is already common practice in livestock feeding. With precision feeding, antibiotic-free rearing is not possible.

Parasites, the immune system and the role of amino acids

Coccidiosis is caused by a single-celled parasite that is normally carried by the Immune system can be easily overcome. Today the Immune system of the animals is weakened during embryonic development due to a lack of angiogenesis (vascularisation).

In 1956, Bruce Glick showed that the lack of an intact and functioning bursa fabricii reduces the effectiveness of antibodies in hatchlings and later in adult birds. In the past, it would have been a joke to treat a piglet for coccidiosis. Today, all piglets in the flocks are treated against coccidiosis. We have the same situation as with chickens, for example.

The reason for this is that the animals' innate cellular immune system does not function due to the aforementioned lysine-arginine antagonism.

In animals with weakened cellular immunitylarge quantities of coccidiostat are administered, which leads to ionophore poisoning. If the coccidiostat is no longer an option, a rethink is required. We carried out an experiment: we provided 1,000 chickens with e1,000 were treated with the same feed but without the coccidiostat. without the drug and 1,000 also without the drug, but with a Fulvic acid-arginine complex added to the feed. The best results were achieved in the last group: no coccidiosis and no poisoning by ionophores.

Avian flu - Covid

Avian influenza remains a persistent problem. The reason for its spread lies in the predisposing factors. These help an opportunistic pathogen to establish the disease in a living organism.

With a well-functioning human immune system, COVID would not be a problem either. COVID is an opportunistic (lives with the organism), facultative pathogen (only causes disease under certain conditions).

If the poultry is infected with the avian influenza virus and it enters the respiratory tract and digestive tract, the animal is defenceless. (The killer function of the macrophages does not work). The "ammunition" in the macrophages' "weapon" is nitric oxide. If they lack this "ammunition" due to lysine-arginine antagonism, the macrophages are helpless against the virus. (Macrophages and natural killer cells produce nitric oxide from arginine with the help of the enzyme iNOS. This triggers the programmed cell death of the virus).

Countries continue to pay hundreds of millions of euros in compensation for bird flu.

The case of threonine and tryptophan

Threonine is an amino acid that counteracts tryptophan. The already poorly functioning tryptophan metabolism is further disrupted by the addition of the free amino acid threonine to the feed.

94% of the tryptophan ingested with food is used for the production of one of our most important coenzymes, NAD. This biochemical pathway is the quinurenine pathway. If it is disrupted, mitochondrial diseases occur in humans. In pigs, this leads to periweaning failure to thrive syndrome (PFTS). 10-15% of piglets in countries with advanced pig breeding are affected.

The inhibition of the kinurenine pathway is caused by the inhibitory effect of the enzyme IDO due to the Glyphosate caused by nitric oxide deficiency and lysine-arginine antagonism.

Tryptophan and phenylalanine are important amino acids in the body. Tryptophan is a precursor of NAD, NADP and serotonin synthesis, while phenylalanine is a precursor of tyrosine. Tyrosine, in turn, is a precursor of dopamine and two tyrosine amino acids together form the thyroid hormone thyroxine.

Both tryptophan and phenylalanine are essential amino acids in animals and humans. The glyphosate content of genetically modified soya blocks the metabolism of amino acids. Some claim that animal products are healthy, even though they contain many glyphosate residues that destroy beneficial bacteria in the human gut flora and inhibit our cytocrome P450 defence enzyme system. Glyphosate destroys the microbiome. There are numerous scientific publications and evidence against glyphosate. We would like to draw your attention to the work of Anthony Samsel and Stephanie Seneff.

Without the Restoration of the microbiome the immune system cannot function. 70 % of our immune system is located in the gut (GALT). The result of years of research is a formulation that contains, among other things, a fulvic acid-arginine complex. Arginine can be absorbed quickly and at 100%. The high content of fulvic acid can restore cellular immunity, as Fulvic acid forms a complex bond with free amino acids (e.g. lysine) so that lysine is not absorbed as free lysine. This cancels out the lysine-arginine antagonism.