What is an autoimmune disease?
An autoimmune disease is a malfunction of the immune system in which the body’s own structures – cells and organs – are attacked. From type 1 diabetes and multiple sclerosis to psoriasis and rheumatism, this can lead to a range of symptoms. Autoimmune diseases are among the fastest-growing diseases today. One of the leading causes of autoimmune disease is a leaky gut syndrome.
What is a leaky gut syndrome?
Leaky gut syndrome is damage to the lining of the intestines. It can be a serious cause of many chronic diseases. Most of them are considered incurable, such as allergies and autoimmune diseases.
What causes leaky gut syndrome?
We eat many plants that have been part of our diet for centuries, but in recent decades they have started to cause health problems. We might ask: if they had no disease-causing effect in the past, why are they causing health problems in some people today?
The answer lies in the modern food environment: the addition of additives to food and the lack of fermentation (traditional methods of cooking and preparation).
For example, the gluten and FODMAP content of Triticum cereals is harmful to the intestinal lining. The WGA protein (lectin with antigenic effect) of wheat, barley and rye triggers autoimmune effects.
Together, these substances cause the leaky gut syndrome.
They lose their harmful, inflammatory and intestinal epithelial cell-damaging effect only during fermentation. Without fermentation, they have a so-called “tight junction” effect: they destroy the junctions between the enterocytes.
How long does the necessary fermentation take?
This fermentation takes 8-16 hours in real sourdough bread. In modern commercial bread with additives, all these substances are absorbed into the intestinal wall without biochemical changes and in an unchanged form.
The body tries to compensate for this and develops a defence strategy, e.g. it protects the enterocytes with a thicker glycocalyx layer if it can produce this protective “sugar coat” shield.
How does your gut defend itself?
Inflammation is always encoded by sugars, for example, the outer lipopolysaccharide layer of gram-negative bacteria or the glycoprotein structure (sugar-protein) of plant lectins. Therefore, the intestine protects the enterocytes with its own “glycocalyx”, a sugar coat. It is a protective shield of sugar against its inflammatory effects.
In the water layer that protects the intestinal wall, the intestine produces a mucus layer that contains beneficial intestinal bacteria.
Fulvicherb-Synergy helps to restore the gut microbiome and so helps with histamine sensitivity.
The integrity of the gut
The integrity of the gut is a very important factor in maintaining balance in the body. The integrity of the gut ensures that what should be absorbed is absorbed.
The mucosal cells on the surface of the intestinal mucosa, the enterocytes, have an independent function. They live for 10-14 days, are born and die. At the age of 1-5 days, they produce intestinal fluid through secretory activity, which is important for good digestion. At 5-10 days of age, they provide ingestive activity.
The exopeptidases at the brush border of the enterocytes are very important enzymes. In the case of lactose intolerance, the enzyme lactase is not produced on the surface of the damaged enterocytes. When the enterocytes are damaged, the entire digestion and absorption process is impaired.
Intestinal circulation, i.e. the opening of the micro capillaries in the intestinal canals, is very important for the development and smooth functioning of the enterocytes. For example, if someone suffers from hypertension, the microcapillaries throughout the body cannot open, including in the intestinal tracts. This is the first help that Fulvicherb-Synergy gives to eliminate leaky gut syndrome because it has a very remarkable effect by promoting NO production.
Fulvicherb-Synergy is very helpful in the production of these two protective layers, the intact enterocytes can produce a large and thick sugar coat. By inhibiting the proliferation of harmful intestinal bacteria and by the nutritive effect of the beneficial intestinal bacteria of apple pectin, the defence mechanism of the mucus layer is significantly improved.
The connection between SIBO and nitric oxide
SIBO stands for Small Intestinal Bacterial Overgrowth and refers to bacterial overgrowth in the small intestine. SIBO is the most common cause of irritable bowel syndrome (IBS) and one of the most overlooked and underdiagnosed conditions. SIBO also contributes to the leaky gut syndrome.
At the junction of the small intestine and the large intestine, there is a valve called the ileocecal valve (or Bauhin’s valve). It is a cap operated by smooth muscle that prevents the bacteria-rich (and very differently composed) contents of the large intestine from being reabsorbed into the specifically bacteria-poor and differently composed small intestine. When this valve fails, it causes the syndrome of bacterial overgrowth of the small intestine.
This condition destroys the protective layers in the small intestine. This can be seen in the phenomenon of flatulence after meals.
Fulvicherb-Synergy helps the ileocecal valve to function properly. (The fulvic acid-arginine complex in Fulvicherb also helps the very small smooth muscles to function properly. It also has a positive effect on reflux by affecting the function of the oesophageal sphincter and diaphragm).
If everyone ate real, additive-free sourdough bread, there probably wouldn’t be as many people with gluten intolerance. The overall condition of the intestinal wall would be much better.
If someone with a healthy gut microbiome occasionally eats pasta or baked goods that have not gone through a fermentation process, the gut’s good defence mechanism of sugar-coat and mucus layer will protect the integrity of the gut wall.
Read the article in German: Ursachen und Lösungen für Autoimmun-Erkrankungen
Read the article in Polish: Przyczyny i rozwiązania dla chorób autoimmunologicznych